FDA Grants Accelerated Approval to Pembrolizumab for HER2-Positive Gastric Cancer

FDA Grants Accelerated Approval to Pembrolizumab for HER2-Positive Gastric Cancer

On May 5, 2021, the U.S. Food and Drug Administration (FDA) granted accelerated approval to pembrolizumab (Keytruda®) in combination with trastuzumab and fluoropyrimidine- and platinum-containing chemotherapy for first-line treatment of patients with locally advanced unresectable or metastatic HER2-positive gastric or gastroesophageal junction (GEJ) adenocarcinoma.

Genomics Test Guides Treatment Decisions for Prostate Cancer

Genomics Test Guides Treatment Decisions for Prostate Cancer

The Decipher genomics test, which measures activity of 22 genes among seven known cancer pathways, independently estimates patients’ risk of prostate cancer metastasis, death, and overall survival and helps identify patients most likely to benefit from hormone therapy, researchers reported in study findings published in JAMA Oncology.

Nursing Leadership Has Space for You and Your Goals

Nursing Leadership Has Space for You and Your Goals

When you picture a nurse leader, what do you see? The thought of being a leader or taking on a formal leadership role can seem intimidating for so many nurses. But age, citizenship status, ethnicity, or gender are strengths, not obstacles. Every nurse enters the profession with the foundation to be a successful leader. 

We Have So Much to Celebrate in Nursing and Cancer Science This Year

We Have So Much to Celebrate in Nursing and Cancer Science This Year

May is the month we celebrate nursing across the world. May 12, Florence Nightingale’s birthday, is International Nurses Day, designated as such since 1974 by the International Council of Nurses. This year’s theme is Nurses: A Voice to Lead, A Vision for Future Health Care in recognition of nursing's role on the front lines of the pandemic.

When Everything Still Isn't Enough

When Everything Still Isn't Enough

Last year, I was involved in the care of Emma (not her real name), a 22-year-old woman with duodenal adenocarcinoma. Cancers of the small intestine are very rare, accounting for less than 1% of all cancers diagnosed in a given year. Because the average age at diagnosis is 66 years, Emma was unusual to have been diagnosed at only 20. But Emma was an exceptional patient in many ways beyond her rare diagnosis: she was remarkably resilient for one so young and came armed with an incredible support system of loved ones.

Cognitive Impairment Is Much More Than “Chemo Brain”

Cancer-related cognitive impairment (CRCI) is a result of a slew of confounding variables, including cancer, its treatments, and other factors. Although the side effect is expected, it doesn’t have to be accepted. Patients have many options to manage CRCI, and nurses have an important role in education, assessment, and referral to support, according to speakers at a session on April 29, 2021, during the 46th Annual ONS Congress™. 

How to Handle Even the Worst Radiation Therapy Side Effects

Some of the most painful side effects of cancer and its treatment occur with radiation therapy. Although patients may find the effects emotionally devastating, nurses can help take a proactive management approach by preparing patients for what’s ahead. Annette Quinn, RN, MSN, from the University of Pittsburgh Hillman Cancer Center, outlined the most common but distressing side effects and tips for managing them during a session held on April 29, 2021, for the 46th Annual ONS Congress™.

The Horizon Looks Promising for Emerging Radiation Therapies in Oncology Care

Cutting-edge advancements in radiation therapy (RT) may allow oncology practitioners to only target the current tumor and avoid damaging healthy tissue. During a session on April 29, 2021, at the ONS 46th Annual Congress, W. Neil Duggar, PhD, DABR, of the University of Mississippi Medical Center, provided an overview of RT from a medical physics perspective, with a focus on how developing technologies may revolutionize care for patients with cancer. 

Here’s Why Oncology Nurses Are Pivotal in Managing Immune-Related Adverse Events

Immune checkpoint inhibitors (ICPIs) mobilize the body’s own immune system to target cancer cells. However, the resulting immune-related adverse events (irAEs) vary in severity and may persist for months or years following treatment.

The Time Is Now to Address Racial Disparities in Oncology Symptom Science

Although cancer mortality in the United States has decreased in most populations, non-Whites still have a disproportionately higher risk, and recent events have raised awareness of racial healthcare disparities. During a session on April 29, 2021, for the ONS 46th Annual Congress™, Margaret Quinn Rosenzweig, PhD, FNP-BC, AOCNP®, FAAN, of the University of Pittsburgh School of Nursing, Susan G. Dorsey, PhD, RN, FAAN, of the University of Maryland School of Nursing, and Angela Starkweather, PhD, ACNP-BC, FAAN, FAANP, of the University of Connecticut School of Nursing and School of Medicine, explored the application of the symptom science model to address the needs of underrepresented patients.