Nurses can attain several levels of practice leadership to grow their professional development, including the clinical nurse specialist (CNS) and the clinical nurse leader (CNL). However, both roles are very different in their daily duties and responsibilities. Nancy Froggatt, MN, RN, CNL, of the Froedtert Hospital in Milwaukee, WI, and Lenise Taylor, MN, RN, AOCNS®, BMTCN®, of the Seattle Cancer Care Alliance and the University of Washington Medical Center in Seattle, WA, provided advice on the CNS and CNL roles and how to assess which might be best for your career.