Bothersome and distressing sexual dysfunction is common in both men and women living with cancer. Treatments can potentially alter a person’s sexual health in the physical, emotional, mental ,and social well-being realms of care. Literature has shown that time constraints and level of comfort with sexual health content are barriers to addressing patients’ sexual health concerns. On Friday, April 12, 2019, at the ONS 44th Annual Congress in Anaheim, CA, speakers provided an overview of sexual health concerns and strategies to assure a positive and respectful approach to female and male patients with cancer who are experiencing them.