Of cancers affecting both men and women, colorectal cancer (CRC) is the second leading killer in the United States. In 2014, according to the Centers for Disease Control and Prevention, 139,992 people in the United States were diagnosed with CRC and 51,651 people died from it. Oncology nurses know that screening tests allow for healthcare providers to remove polyps before they become cancer or identify CRC in its earliest, most treatable stages. Clearly, screening is key to preventing CRC, most insurance plans cover screening, and patients now have more screening test options than ever. So why is CRC still so common? Why do people we know and care about still get this disease?